Literatures refer to tsRNA over years

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tRNA-derived fragments (tRFs): establishing their turf in post-transcriptional gene regulation
Cell Mol Life Sci.  2021 Jan
DOI: 10.1007/s00018-020-03720-7
PMID: 33388834

tRNA-derived fragments: Mechanisms underlying their regulation of gene expression and potential applications as therapeutic targets in cancers and virus infections
Theranostics.  2021 Jan; 11(1):461-469
DOI: 10.7150/thno.51963
PMID: 33391486

A comprehensive expression profile of tRNA-derived fragments in papillary thyroid cancer
J Clin Lab Anal.  2020 Dec; e23664
DOI: 10.1002/jcla.23664
PMID: 33332661

Genome-wide analysis of hippocampal transfer RNA-derived small RNAs identifies new potential therapeutic targets of Bushen Tiansui formula against Alzheimer's disease
J Integr Med.  2020 Dec; S2095-4964(20)30137-0
DOI: 10.1016/j.joim.2020.12.005
PMID: 33334712

Transfer RNA fragments replace microRNA regulators of the cholinergic poststroke immune blockade
Proc Natl Acad Sci U S A.  2020 Dec; 202013542
DOI: 10.1073/pnas.2013542117
PMID: 33288717

tRNA-Derived Fragments (tRFs) in Bladder Cancer: Increased 5'-tRF-LysCTT Results in Disease Early Progression and Patients' Poor Treatment Outcome
Cancers (Basel).  2020 Dec; 12(12):3661
DOI: 10.3390/cancers12123661
PMID: 33291319

tRNA-Derived Fragments in Alzheimer's Disease: Implications for New Disease Biomarkers and Neuropathological Mechanisms
J Alzheimers Dis.  2020 Dec
DOI: 10.3233/JAD-200917
PMID: 33337366

Differential expression of transfer RNA-derived small RNAs in IgA nephropathy
Medicine (Baltimore).  2020 Nov; 99(48):e23437
DOI: 10.1097/MD.0000000000023437
PMID: 33235128

Expression Pattern of Seminal Plasma Extracellular Vesicle Small RNAs in Boar Semen
Front Vet Sci.  2020 Nov; 7:585276
DOI: 10.3389/fvets.2020.585276
PMID: 33263017

Integrative analysis of transcriptomes highlights potential functions of transfer-RNA-derived small RNAs in experimental intracerebral hemorrhage
Aging (Albany NY).  2020 Nov; 12(22):22794-22813
DOI: 10.18632/aging.103938
PMID: 33203799

Mucosal immunity and tRNA, tRF, and tiRNA
J Mol Med (Berl).  2020 Nov
DOI: 10.1007/s00109-020-02008-4
PMID: 33200232

Peripheral blood non-canonical small non-coding RNAs as novel biomarkers in lung cancer
Mol Cancer.  2020 Nov; 19(1):159
DOI: 10.1186/s12943-020-01280-9
PMID: 33176804

Small RNA sequencing reveals a novel tsRNA-06018 playing an important role during adipogenic differentiation of hMSCs
J Cell Mol Med.  2020 Nov; 24(21):12736-12749
DOI: 10.1111/jcmm.15858
PMID: 32939933

Systematic Analysis of tRNA-Derived Small RNAs Discloses New Therapeutic Targets of Caloric Restriction in Myocardial Ischemic Rats
Front Cell Dev Biol.  2020 Nov; 8:568116
DOI: 10.3389/fcell.2020.568116
PMID: 33224944

Transfer RNA-Derived Small RNAs: Another Layer of Gene Regulation and Novel Targets for Disease Therapeutics
Mol Ther.  2020 Nov; 28(11):2340-2357
DOI: 10.1016/j.ymthe.2020.09.013
PMID: 32956625

Transfer-RNA-Derived Fragments Are Potential Prognostic Factors in Patients with Squamous Cell Carcinoma of the Head and Neck
Genes (Basel).  2020 Nov; 11(11):1344
DOI: 10.3390/genes11111344
PMID: 33202812

Comprehensively Identifying the Key tRNA-Derived Fragments and Investigating Their Function in Gastric Cancer Processes
Onco Targets Ther.  2020 Oct; 13:10931-10943
DOI: 10.2147/OTT.S266130
PMID: 33149609

Osteogenic Effect of tsRNA-10277-Loaded Exosome Derived from Bone Mesenchymal Stem Cells on Steroid-Induced Osteonecrosis of the Femoral Head
Drug Des Devel Ther.  2020 Oct; 14:4579-4591
DOI: 10.2147/DDDT.S258024
PMID: 33149555

The role of Transfer RNA-Derived Small RNAs (tsRNAs) in Digestive System Tumors
J Cancer.  2020 Oct; 11(24):7237-7245
DOI: 10.7150/jca.46055
PMID: 33193887

tRFTar: Prediction of tRF-target gene interactions via systemic re-analysis of Argonaute CLIP-seq datasets
Methods.  2020 Oct; S1046-2023(20)30220-6
DOI: 10.1016/j.ymeth.2020.10.006
PMID: 33045361

tRFtarget: a database for transfer RNA-derived fragment targets
Nucleic Acids Res.  2020 Oct; gkaa831
DOI: 10.1093/nar/gkaa831
PMID: 33035346

tRNA Fragments Populations Analysis in Mutants Affecting tRNAs Processing and tRNA Methylation
Front Genet.  2020 Oct; 11:518949
DOI: 10.3389/fgene.2020.518949
PMID: 33193603

Differences in small noncoding RNAs profile between bull X and Y sperm
PeerJ.  2020 Sep; 8:e9822
DOI: 10.7717/peerj.9822
PMID: 32999759

Emerging Roles of tRNAs in RNA Virus Infections.
Trends Biochem Sci.  2020 Sep; 45(9):794-805
DOI: 10.1016/j.tibs.2020.05.007
PMID: 32505636

Mycobacterium tuberculosis infection drives mitochondria-biased dysregulation of host tRNA-derived fragments
J Infect Dis.  2020 Sep; jiaa596
DOI: 10.1093/infdis/jiaa596
PMID: 32959876

On the expanding roles of tRNA fragments in modulating cell behavior.
Nucleic Acids Res.  2020 Sep; gkaa657
DOI: 10.1093/nar/gkaa657
PMID: 32890397

Osteoblastogenesis Alters Small RNA Profiles in EVs Derived from Bone Marrow Stem Cells (BMSCs) and Adipose Stem Cells (ASCs)
Biomedicines.  2020 Sep; 8(10):387
DOI: 10.3390/biomedicines8100387
PMID: 32998458

Plasma tRNA Fragments Derived from 5' Ends as Novel Diagnostic Biomarkers for Early-Stage Breast Cancer.
Mol Ther Nucleic Acids.  2020 Sep; 21:954-964
DOI: 10.1016/j.omtn.2020.07.026
PMID: 32814252

Transfer RNA-derived small RNAs: potential applications as novel biomarkers for disease diagnosis and prognosis
Ann Transl Med.  2020 Sep; 8(17):1092
DOI: 10.21037/atm-20-2797
PMID: 33145311

cfRNAs as biomarkers in oncology - still experimental or applied tool for personalized medicine already?
Rep Pract Oncol Radiother.  2020 Sep; 25(5):783-792
DOI: 10.1016/j.rpor.2020.07.007
PMID: 32904167

tRNA-Derived Small RNAs and Their Potential Roles in Cardiac Hypertrophy
Front Pharmacol.  2020 Sep; 11:572941
DOI: 10.3389/fphar.2020.572941
PMID: 33041815

tRNA-Derived Small RNAs: Novel Epigenetic Regulators
Cancers (Basel).  2020 Sep; 12(10):2773
DOI: 10.3390/cancers12102773
PMID: 32992597

tRNA-derived RNA fragments in cancer: current status and future perspectives.
J Hematol Oncol.  2020 Sep; 13(1):121
DOI: 10.1186/s13045-020-00955-6
PMID: 32887641

A novel tsRNA-16902 regulating the adipogenic differentiation of human bone marrow mesenchymal stem cells
Stem Cell Res Ther.  2020 Aug; 11(1):365
DOI: 10.1186/s13287-020-01882-6
PMID: 32831139

A novel tsRNA-16902 regulating the adipogenic differentiation of human bone marrow mesenchymal stem cells.
Stem Cell Res Ther.  2020 Aug; 11(1):365
DOI: 10.1186/s13287-020-01882-6
PMID: 32831139

A novel, mitochondrial, internal tRNA-derived RNA fragment possesses clinical utility as a molecular prognostic biomarker in chronic lymphocytic leukemia.
Clin Biochem.  2020 Aug; S0009-9120(20)30794-3
DOI: 10.1016/j.clinbiochem.2020.07.005
PMID: 32745483

Arabidopsis tRNA-derived fragments as potential modulators of translation.
RNA Biol.  2020 Aug; 17(8):1137-1148
DOI: 10.1080/15476286.2020.1722514
PMID: 31994438

Emerging roles of novel small non-coding regulatory RNAs in immunity and cancer.
RNA Biol.  2020 Aug; 17(8):1196-1213
DOI: 10.1080/15476286.2020.1737442
PMID: 32186461

Extracellular tRNAs and tRNA-derived fragments.
RNA Biol.  2020 Aug; 17(8):1149-1167
DOI: 10.1080/15476286.2020.1729584
PMID: 32070197

Extracellular vesicles produced by the protozoan parasite Trichomonas vaginalis contain a preferential cargo of tRNA-derived small RNAs.
Int J Parasitol.  2020 Aug; S0020-7519(20)30237-X
DOI: 10.1016/j.ijpara.2020.07.003
PMID: 32822680

Fragmentation of extracellular ribosomes and tRNAs hshapes the extracellular RNAome.
Nucleic Acids Res.  2020 Aug; gkaa674
DOI: 10.1093/nar/gkaa674
PMID: 32785615

Inferring Targeting Modes of Argonaute-loaded tRNA Fragments.
RNA Biol.  2020 Aug; 17(8):1070-1080
DOI: 10.1080/15476286.2019.1676633
PMID: 31613177

Interplay of tRNA-Derived Fragments and T Cell Activation in Breast Cancer Patient Survival.
Cancers (Basel).  2020 Aug; 12(8):E2230
DOI: 10.3390/cancers12082230
PMID: 32785169

Isolation and initial structure-functional characterization of endogenous tRNA-derived stress-induced RNAs.
RNA Biol.  2020 Aug; 17(8):1116-1124
DOI: 10.1080/15476286.2020.1732702
PMID: 32116132

Modulation of mammalian translation by a ribosome-associated tRNA half.
RNA Biol.  2020 Aug; 17(8):1125-1136
DOI: 10.1080/15476286.2020.1744296
PMID: 32223506

Noncanonical Roles of tRNAs: tRNA Fragments and Beyond.
Annu Rev Genet.  2020 Aug
DOI: 10.1146/annurev-genet-022620-101840
PMID: 32841070

Noncoding RNAs in Cardiovascular Disease: Current Knowledge, Tools and Technologies for Investigation, and Future Directions.
Circ Genom Precis Med.  2020 Aug; 13(4):e000062
DOI: 10.1161/HCG.0000000000000062
PMID: 32812806

Novel insights into the emerging roles of tRNA-derived fragments in mammalian development.
RNA Biol.  2020 Aug; 17(8):1214-1222
DOI: 10.1080/15476286.2020.1732694
PMID: 32116113

OncotRF: an online resource for exploration of tRNA-derived fragments in human cancers.
RNA Biol.  2020 Aug; 17(8):1081-1091
DOI: 10.1080/15476286.2020.1776506
PMID: 32597311

Oxidative stress enhances the expression of 2',3'-cyclic phosphate-containing RNAs.
RNA Biol.  2020 Aug; 17(8):1081-1091
DOI: 10.1080/15476286.2020.1776506
PMID: 32397797

Production and purification of endogenously modified tRNA-derived small RNAs.
RNA Biol.  2020 Aug; 17(8):1104-1115
DOI: 10.1080/15476286.2020.1733798
PMID: 32138588

Small RNA modifications in Alzheimer's disease.
Neurobiol Dis.  2020 Aug; 145:105058
DOI: 10.1016/j.nbd.2020.105058
PMID: 32835860

Stable tRNA halves can be sorted into extracellular vesicles and delivered to recipient cells in a concentration-dependent manner.
RNA Biol.  2020 Aug; 17(8):1168-1182
DOI: 10.1080/15476286.2019.1708548
PMID: 31885318

The regulatory world of tRNA fragments beyond canonical tRNA biology.
RNA Biol.  2020 Aug; 17(8):1057-1059
DOI: 10.1080/15476286.2020.1785196
PMID: 32715957

The stress specific impact of ALKBH1 on tRNA cleavage and tiRNA generation.
RNA Biol.  2020 Aug; 17(8):1092-1103
DOI: 10.1080/15476286.2020.1779492
PMID: 32521209

tRNA-derived fragments (tRFs) regulate post-transcriptional gene expression via AGO-dependent mechanism in IL-1b stimulated chondrocytes.
Osteoarthritis Cartilage.  2020 Aug; 28(8):1102-1110
DOI: 10.1016/j.joca.2020.04.014
PMID: 32407895

tRNA-derived fragments and microRNAs in the maternal-fetal interface of a mouse maternal-immune-activation autism model.
RNA Biol.  2020 Aug; 17(8):1183-1195
DOI: 10.1080/15476286.2020.1721047
PMID: 31983265

A tRNA-derived fragment (tRF-3001b) aggravates the development of nonalcoholic fatty liver disease by inhibiting autophagy.
Life Sci.  2020 Jul; 257:118125
DOI: 10.1016/j.lfs.2020.118125
PMID: 32702444

Identification of tRFs and phasiRNAs in tomato (Solanum lycopersicum) and their responses to exogenous abscisic acid.
BMC Plant Biol.  2020 Jul; 20(1):320
DOI: 10.1186/s12870-020-02528-8
PMID: 32635887

Identification of tRNA-derived fragments and their potential roles in diabetic cataract rats.
Epigenomics.  2020 Jul
DOI: 10.2217/epi-2020-0193
PMID: 32700969

Processing by RNase 1 forms tRNA halves and distinct Y RNA fragments in the extracellular environment.
Nucleic Acids Res.  2020 Jul; gkaa526
DOI: 10.1093/nar/gkaa526
PMID: 32609822

Small RNA Sequencing Reveals Transfer RNA-derived Small RNA Expression Profiles in Retinal Neovascularization.
Int J Med Sci.  2020 Jul; 17(12):1713-1722
DOI: 10.7150/ijms.46209
PMID: 32714074

The nuclear and organellar tRNA-derived RNA fragment population in Arabidopsis thaliana is highly dynamic.
Nucleic Acids Res.  2020 Jul; gkaa651
DOI: 10.1093/nar/gkaa651
PMID: 32735649

tRNAArg-Derived Fragments Can Serve as Arginine Donors for Protein Arginylation.
Cell Chem Biol.  2020 Jul; 27(7):839-849
DOI: 10.1016/j.chembiol.2020.05.013
PMID: 32553119

5' tRNA halves are highly expressed in the primate hippocampus and might sequence-specifically regulate gene expression.
RNA.  2020 Jun; 26(6):694-707
DOI: 10.1261/rna.073395.119
PMID: 32144192

A 3'-tRNA-derived fragment enhances cell proliferation, migration and invasion in gastric cancer by targeting FBXO47.
Arch Biochem Biophys.  2020 Jun; 690:108467
DOI: 10.1016/j.abb.2020.108467
PMID: 32592804

Action mechanisms and research methods of tRNA-derived small RNAs.
Signal Transduct Target Ther.  2020 Jun; 5(1):109
DOI: 10.1038/s41392-020-00217-4
PMID: 32606362

Early cleavage of preimplantation embryos is regulated by tRNAGln-TTG-derived small RNAs present in mature spermatozoa.
J Biol Chem.  2020 Jun; jbc.RA120.013003
DOI: 10.1074/jbc.RA120.013003
PMID: 32487749

Identification of tRNA-derived small RNA (tsRNA) responsive to the tumor suppressor, RUNX1, in breast cancer.
J Cell Physiol.  2020 Jun; 235(6):5318-5327
DOI: 10.1002/jcp.29419
PMID: 31919859

Predicting the presence of breast cancer using circulating small RNAs, including those in the extracellular vesicles.
Cancer Sci.  2020 Jun; 111(6):2104-2115
DOI: 10.1111/cas.14393
PMID: 32215990

The Long and Short of It: The Emerging Roles of Non-Coding RNA in Small Extracellular Vesicles.
Cancers (Basel).  2020 Jun; 12(6):1445
DOI: 10.3390/cancers12061445
PMID: 32498257

The potential role of tRNAs and small RNAs derived from tRNAs in the occurrence and development of systemic lupus erythematosus.
Biochem Biophys Res Commun.  2020 Jun; 527(2):561-567
DOI: 10.1016/j.bbrc.2020.04.114
PMID: 32423797

eIF4G has intrinsic G-quadruplex binding activity that is required for tiRNA function.
Nucleic Acids Res.  2020 Jun; 48(11):6223-6233
DOI: 10.1093/nar/gkaa336
PMID: 32374873

tRFs as Potential Exosome tRNA-Derived Fragment Biomarkers for Gastric Carcinoma.
Clin Lab.  2020 Jun
DOI: 10.7754/Clin.Lab.2019.190811
PMID: 32538051

tRNA-Derived Fragments in Podocytes with Adriamycin-Induced Injury Reveal the Potential Mechanism of Idiopathic Nephrotic Syndrome.
Biomed Res Int.  2020 Jun; 2020:7826763
DOI: 10.1155/2020/7826763
PMID: 32685525

A Comprehensive Repertoire of Transfer RNA-Derived Fragments and Their Regulatory Networks in Colorectal Cancer.
J Comput Biol.  2020 May
DOI: 10.1089/cmb.2019.0305
PMID: 32392430

A Twist between ROS and Sperm-Mediated Intergenerational Epigenetic Inheritance.
Mol Cell.  2020 May; 78(3):371-373
DOI: 10.1016/j.molcel.2020.04.003
PMID: 32386538

Male reproductive health and intergenerational metabolic responses from a small RNA perspective.
J Intern Med.  2020 May
DOI: 10.1111/joim.13096
PMID: 32415866

Quantification of tRNA fragments by electrochemical direct detection in small volume biofluid samples.
Sci Rep.  2020 May; 10(1):7516
DOI: 10.1038/s41598-020-64485-4
PMID: 32371908

Relationship between tRNA-derived fragments and human cancers.
Int J Cancer.  2020 May
DOI: 10.1002/ijc.33107
PMID: 32427348

Stress Induced tRNA Halves (tiRNAs) as Biomarkers for Stroke and Stroke Therapy; Pre-clinical Study.
Neuroscience.  2020 May; 434:44-54
DOI: 10.1016/j.neuroscience.2020.03.018
PMID: 32200075

Tyrosine pre-transfer RNA fragments are linked to p53-dependent neuronal cell death via PKM2.
Biochem Biophys Res Commun.  2020 May; 525(3):726-732
DOI: 10.1016/j.bbrc.2020.02.157
PMID: 32143824

mmannot: How to improve small-RNA annotation?
PLoS One.  2020 May; 15(5):e0231738
DOI: 10.1371/journal.pone.0231738
PMID: 32463818

Angiogenin and tRNA fragments in Parkinson's disease and neurodegeneration.
Acta Pharmacol Sin.  2020 Apr; 41(4):442-446
DOI: 10.1038/s41401-020-0375-9
PMID: 32144338

Comprehensive profiling of Small RNAs in human embryo-conditioned culture media by improved sequencing and quantitative PCR methods.
Syst Biol Reprod Med.  2020 Apr; 66(2):129-139
DOI: 10.1080/19396368.2020.1716108
PMID: 32053759

A comprehensive overview of bull sperm-borne small non-coding RNAs and their diversity across breeds.
Epigenetics Chromatin.  2020 Mar; 13(1):19
DOI: 10.1186/s13072-020-00340-0
PMID: 32228651

Non-Coding RNAs and Their Role in Respiratory Syncytial Virus (RSV) and Human Metapneumovirus (hMPV) Infections.
Viruses.  2020 Mar; 12(3):345
DOI: 10.3390/v12030345
PMID: 32245206

Phase Separation and Disorder-to-Order Transition of Human Brain Expressed X-Linked 3 (hBEX3) in the Presence of Small Fragments of tRNA.
J Mol Biol.  2020 Mar; 432(7):2319-2348
DOI: 10.1016/j.jmb.2020.02.030
PMID: 32142787

Serum tRNA-derived Fragments (tRFs) as Potential Candidates for Diagnosis of Nontriple Negative Breast Cancer.
J Cell Physiol.  2020 Mar; 235(3):2809-2824
DOI: 10.1002/jcp.29185
PMID: 31535382

Activation of Transposable Elements in Immune Cells of Fibromyalgia Patients.
Int J Mol Sci.  2020 Feb; 21(4):1366
DOI: 10.3390/ijms21041366
PMID: 32085571

Expression profiles of tRNA-derived fragments and their potential roles in ovarian endometriosis.
Epigenomics.  2020 Feb; 12(3):183-197
DOI: 10.2217/epi-2019-0277
PMID: 31845823

Non-coding RNAs Shaping Muscle.
Front Cell Dev Biol.  2020 Feb; 7:394
DOI: 10.3389/fcell.2019.00394
PMID: 32117954

Pathological Significance of tRNA-derived Small RNAs in Neurological Disorders.
Neural Regen Res.  2020 Feb; 15(2):212-221
DOI: 10.4103/1673-5374.265560
PMID: 31552886

Role of Non-Coding RNAs in the Development of Targeted Therapy and Immunotherapy Approaches for Chronic Lymphocytic Leukemia.
J Clin Med.  2020 Feb; 9(2):593
DOI: 10.3390/jcm9020593
PMID: 32098192

Role of tRNA-derived fragments in cancer: novel diagnostic and therapeutic targets tRFs in cancer.
Am J Cancer Res.  2020 Feb; 10(2):393-402
PMID: 32195016

tiRNAs: A Novel Class of Small Noncoding RNAs That Helps Cells Respond to Stressors and Plays Roles in Cancer Progression.
J Cell Physiol.  2020 Feb; 235(2):683-690
DOI: 10.1002/jcp.29057
PMID: 31286522

Differential Expression Profiles and Functional Prediction of tRNA-Derived Small RNAs in Rats After Traumatic Spinal Cord Injury.
Front Mol Neurosci.  2020 Jan; 0.726388889
DOI: 10.3389/fnmol.2019.00326
PMID: 31998075

IsomiRs and tRNA-derived Fragments Are Associated With Metastasis and Patient Survival in Uveal Melanoma.
Pigment Cell Melanoma Res.  2020 Jan; 33(1):52-62
DOI: 10.1111/pcmr.12810
PMID: 31283110

tRNA Cleavage: A New Insight.
Neural Regen Res.  2020 Jan; 15(1):47-52
DOI: 10.4103/1673-5374.264447
PMID: 31535642

tRNA-derived small RNAs: A novel class of small RNAs in human hypertrophic scar fibroblasts.
Int J Mol Med.  2020 Jan; 45(1):115-130
DOI: 10.3892/ijmm.2019.4411
PMID: 31939611

A Novel 3'-tRNA-Glu-derived Fragment Acts as a Tumor Suppressor in Breast Cancer by Targeting Nucleolin.
FASEB J.  2019 Dec; 33(12):13228-13240
DOI: 10.1096/fj.201900382RR
PMID: 31560576

A tRNA-Derived Small RNA Regulates Ribosomal Protein S28 Protein Levels after Translation Initiation in Humans and Mice.
Cell Rep.  2019 Dec; 29(12):3816-3824
DOI: 10.1016/j.celrep.2019.11.062
PMID: 31851915

Comparative Analysis of Biochemical Biases by Ligation- and Template-Switch-Based Small RNA Library Preparation Protocols.
Clin Chem.  2019 Dec; 65(12):1581-1591
DOI: 10.1373/clinchem.2019.305045
PMID: 31645340

Control of Noncoding RNA Production and Histone Levels by a 5' tRNA Fragment.
Genes Dev.  2019 Dec; 34(1-2):118-131
DOI: 10.1101/gad.332783.119
PMID: 31831626

Human sperm displays rapid responses to diet.
PLoS Biol.  2019 Dec; 17(12):e3000559
DOI: 10.1371/journal.pbio.3000559
PMID: 31877125

Identification of a Novel, Internal tRNA-derived RNA Fragment as a New Prognostic and Screening Biomarker in Chronic Lymphocytic Leukemia, Using an Innovative Quantitative Real-Time PCR Assay.
Leuk Res.  2019 Dec; 87:106234
DOI: 10.1016/j.leukres.2019.106234
PMID: 31669784

Small noncoding RNA discovery and profiling with sRNAtools based on high-throughput sequencing.
Brief Bioinform.  2019 Dec; bbz151
DOI: 10.1093/bib/bbz151
PMID: 31885040

tRNA-derived Fragments From the Sus Scrofa Tissues Provide Evidence of Their Conserved Role in Mammalian Development.
Biochem Biophys Res Commun.  2019 Dec; 520(3):514-519
DOI: 10.1016/j.bbrc.2019.10.062
PMID: 31610915

A Molecular Signature of Three tRNA-Derived RNA Fragments May Discriminate Smoldering from Symptomatic Multiple Myeloma Patients.
Blood.  2019 Nov; 134:5528
DOI: 10.1182/blood-2019-129082

Aberrantly Expressed snoRNA, snRNA, piRNA and tRFs in Canine Melanoma.
Vet Comp Oncol.  2019 Nov
DOI: 10.1111/vco.12558
PMID: 31769925

Angiogenin Generates Specific Stress-Induced tRNA Halves and Is Not Involved in tRF-3-mediated Gene Silencing.
J Biol Chem.  2019 Nov; 294(45):16930-16941
DOI: 10.1074/jbc.RA119.009272
PMID: 31582561

Comparative Analysis of Small RNAs Released by the Filarial Nematode Litomosoides Sigmodontis in Vitro and in Vivo.
PLoS Negl Trop Dis.  2019 Nov; 13(11):e0007811
DOI: 10.1371/journal.pntd.0007811
PMID: 31770367

Differential Expressions of microRNAs and Transfer RNA-derived Small RNAs: Potential Targets of Choroidal Neovascularization.
Curr Eye Res.  2019 Nov; 44(11):1226-1235
DOI: 10.1080/02713683.2019.1625407
PMID: 31136199

Dysregulation of Different Classes of tRNA Fragments in Chronic Lymphocytic Leukemia.
Proc Natl Acad Sci U S A.  2019 Nov; 116(48):24252-24258
DOI: 10.1073/pnas.1913695116
PMID: 31723042

Identification of Functional tRNA-derived Fragments in Senescence-Accelerated Mouse Prone 8 Brain.
Aging (Albany NY).  2019 Nov; 11(22):10485-10498
DOI: 10.18632/aging.102471
PMID: 31746776

Niche Transfer of Small Non-Coding RNAs Regulates Hematopoietic Response to Stress.
Blood.  2019 Nov; 134:1207
DOI: 10.1182/blood-2019-124794

Biochemical Properties and Progress in Cancers of tRNA-derived Fragments.
J Cell Biochem.  2019 Oct; 121(3):2058-2063
DOI: 10.1002/jcb.29492
PMID: 31674076

Expression Profile of tRNA-derived Fragments and Their Potential Roles in Human Varicose Veins.
Mol Med Rep.  2019 Oct; 20(4):3191-3201
DOI: 10.3892/mmr.2019.10544
PMID: 31432124

Identification of a Novel tRNA-derived RNA Fragment Exhibiting High Prognostic Potential in Chronic Lymphocytic Leukemia.
Hematol Oncol.  2019 Oct; 37(4):498-504
DOI: 10.1002/hon.2616
PMID: 30945323

Maternal Circulating Syncytiotrophoblast-Derived Extracellular Vesicles Contain Biologically Active 5'-tRNA Halves.
Biochem Biophys Res Commun.  2019 Oct; 518(1):107-113
DOI: 10.1016/j.bbrc.2019.08.015
PMID: 31405560

Regulation of La/SSB-dependent Viral Gene Expression by pre-tRNA 3' Trailer-Derived tRNA Fragments.
Nucleic Acids Res.  2019 Oct; 47(18):9888-9901
DOI: 10.1093/nar/gkz732
PMID: 31504775

Transfer RNA-Derived Small Non-Coding RNA: Dual Regulator of Protein Synthesis.
Mol Cells.  2019 Oct; 42(10):687-692
DOI: 10.14348/molcells.2019.0214
PMID: 31656062

tRNA-derived Fragments (tRFs) Contribute to Podocyte Differentiation.
Biochem Biophys Res Commun.  2019 Oct; 521(1):1-8
DOI: 10.1016/j.bbrc.2019.09.009
PMID: 31629473

Angiogenin Promotes Colorectal Cancer Metastasis via tiRNA Production.
Int J Cancer.  2019 Sep; 145(5):1395-1407
DOI: 10.1002/ijc.32245
PMID: 30828790

Expression Profile of tRNA-derived Fragments in Pancreatic Cancer.
Oncol Lett.  2019 Sep; 18(3):3104-3114
DOI: 10.3892/ol.2019.10601
PMID: 31452788

Identified Hybrid tRNA Structure Genes in Archaeal Genome.
Iran J Biotechnol.  2019 Sep; 17(3):e2254
DOI: 10.29252/ijb.2254
PMID: 32195286

Profiling of tRNA Halves and YRNA Fragments in Serum and Tissue From Oral Squamous Cell Carcinoma Patients Identify Key Role of 5' tRNA-Val-CAC-2-1 Half.
Front Oncol.  2019 Sep; 1.040972222
DOI: 10.3389/fonc.2019.00959
PMID: 31616639

The MELAS Mutation m.3243A>G Alters the Expression of Mitochondrial tRNA Fragments.
Biochim Biophys Acta Mol Cell Res.  2019 Sep; 1866(9):1433-1449
DOI: 10.1016/j.bbamcr.2019.06.004
PMID: 31195049

A tRNA Fragment, 5'-tiRNA Val, Suppresses the Wnt/beta-catenin Signaling Pathway by Targeting FZD3 in Breast Cancer.
Cancer Lett.  2019 Aug; 457:60-73
DOI: 10.1016/j.canlet.2019.05.007
PMID: 31078732

Bioengineering of a Single Long Noncoding RNA Molecule That Carries Multiple Small RNAs.
Appl Microbiol Biotechnol.  2019 Aug; 103(15):6107-6117
DOI: 10.1007/s00253-019-09934-5
PMID: 31187211

Cell Cycle-Dependent Regulation and Function of ARGONAUTE1 in Plants.
Plant Cell.  2019 Aug; 31(8):1734-1750
DOI: 10.1105/tpc.19.00069
PMID: 31189739

Identification of tRNA-Derived Fragments Expression Profile in Breast Cancer Tissues.
Curr Genomics.  2019 Apr; 20(3):199-213
DOI: 10.2174/1389202920666190326145459
PMID: 31929727

Identification of tRNA-derived Fragments in Colon Cancer by Comprehensive Small RNA Sequencing.
Oncol Rep.  2019 Aug; 42(2):735-744
DOI: 10.3892/or.2019.7178
PMID: 31173257

Rhizobial tRNA-derived Small RNAs Are Signal Molecules Regulating Plant Nodulation.
Science.  2019 Aug; 365(6456):919-922
DOI: 10.1126/science.aav8907
PMID: 31346137

TRNA-derived Fragments as Sex-Dependent Circulating Candidate Biomarkers for Parkinson's Disease.
Parkinsonism Relat Disord.  2019 Aug; 65:203-209
DOI: 10.1016/j.parkreldis.2019.05.035
PMID: 31402278

tRNA-derived Fragment tRF-03357 Promotes Cell Proliferation, Migration and Invasion in High-Grade Serous Ovarian Cancer.
Onco Targets Ther.  2019 Aug; 12:6371-6383
DOI: 10.2147/OTT.S206861
PMID: 31496739

Complement C3 Activation Regulates the Production of tRNA-derived Fragments Gly-tRFs and Promotes Alcohol-Induced Liver Injury and Steatosis.
Cell Res.  2019 Jul; 29(7):548-561
DOI: 10.1038/s41422-019-0175-2
PMID: 31076642

Cooperative 2'-O-methylation of the Wobble Cytidine of Human Elongator tRNA-Met(CAT) by a Nucleolar and a Cajal Body-Specific Box C/D RNP.
Genes Dev.  2019 Jul; 33(13-14):741-746
DOI: 10.1101/gad.326363.119
PMID: 31171702

Dynamic Expression of tRNA-derived Small RNAs Define Cellular States.
EMBO Rep.  2019 Jul; 20(7):e47789
DOI: 10.15252/embr.201947789
PMID: 31267708

Profile Analysis Reveals Transfer RNA Fragments Involved in Mesangial Cells Proliferation.
Biochem Biophys Res Commun.  2019 Jul; 514(4):1101-1107
DOI: 10.1016/j.bbrc.2019.04.022
PMID: 31097225

tRNA-Derived Small Non-Coding RNAs as Novel Epigenetic Molecules Regulating Adipogenesis.
Biomolecules.  2019 Jul; 9(7):274
DOI: 10.3390/biom9070274
PMID: 31336727

tiRNAs as a Novel Biomarker for Cell Damage Assessment in in Vitro Ischemia-Reperfusion Model in Rat Neuronal PC12 Cells.
Brain Res.  2019 Jul; 1714:8-17
DOI: 10.1016/j.brainres.2019.02.019
PMID: 30779912

Hypoxia-induced tRNA-derived fragments, novel regulatory factor for doxorubicin resistance in triple-negative breast cancer.
J Cell Physiol.  2019 Jun; 234(6):8740-8751
DOI: 10.1002/jcp.27533
PMID: 30362543

Physical and Molecular Landscapes of Mouse Glioma Extracellular Vesicles Define Heterogeneity.
Cell Rep.  2019 Jun; 27(13):3972-3987
DOI: 10.1016/j.celrep.2019.05.089
PMID: 31242427

Small RNAs in Rat Sperm Are a Predictive and Sensitive Biomarker of Exposure to the Testicular Toxicant Ethylene Glycol Monomethyl Ether.
Toxicol Sci.  2019 Jun; 169(2):399-408
DOI: 10.1093/toxsci/kfz041
PMID: 30768127

Using tRNA Halves as Novel Biomarkers for the Diagnosis of Gastric Cancer.
Cancer Biomark.  2019 Jun; 25(2):169-176
DOI: 10.3233/CBM-182184
PMID: 31104009

tRNA Fragments Show Intertwining With mRNAs of Specific Repeat Content and Have Links to Disparities.
Cancer Res.  2019 Jun; 79(12):3034-3049
DOI: 10.1158/0008-5472.CAN-19-0789
PMID: 30996049

tRNA-derived Fragments and tRNA Halves: The New Players in Cancers.
Cancer Lett.  2019 Jun; 452:31-37
DOI: 10.1016/j.canlet.2019.03.012
PMID: 30905816

Angiogenin-mediated tRNA cleavage as a novel feature of stored red blood cells.
Br J Haematol.  2019 May; 185(4):760-764
DOI: 10.1111/bjh.15605
PMID: 30368767

Expression Analysis of Transfer RNA-derived Fragments in the Blood of Patients With Moyamoya Disease: A Preliminary Study.
Mol Med Rep.  2019 May; 19(5):3564-3574
DOI: 10.3892/mmr.2019.10024
PMID: 30896793

Maternal Overnutrition Programs Hedonic and Metabolic Phenotypes Across Generations Through Sperm tsRNAs.
Proc Natl Acad Sci U S A.  2019 May; 116(21):10547-10556
DOI: 10.1073/pnas.1820810116
PMID: 31061112

Mature Sperm small-RNA Profile in the Sparrow: Implications for Transgenerational Effects of Age on Fitness.
Environ Epigenet.  2019 May; 5(2):dvz007
DOI: 10.1093/eep/dvz007
PMID: 31139435

Non-Coding RNAs in Caenorhabditis elegans Aging.
Mol Cells.  2019 May; 42(5):379-385
DOI: 10.14348/molcells.2019.0077
PMID: 31094164

Small Non-Coding RNA and Colorectal Cancer.
J Cell Mol Med.  2019 May; 23(5):3050-3057
DOI: 10.1111/jcmm.14209
PMID: 30801950

Small RNA Sequencing Reveals a Novel tsRNA-26576 Mediating Tumorigenesis of Breast Cancer.
Cancer Manag Res.  2019 May; 11:3945-3956
DOI: 10.2147/CMAR.S199281
PMID: 31118807

Analysis of tRNA Halves (tsRNAs) in Serum From Cattle Challenged With Bovine Viral Diarrhea Virus.
Genet Mol Biol.  2019 Apr; 42(2):374-379
DOI: 10.1590/1678-4685-GMB-2018-0019
PMID: 31259361

Differential Expression of Human tRNA Genes Drives the Abundance of tRNA-derived Fragments.
Proc Natl Acad Sci U S A.  2019 Apr; 116(17):8451-8456
DOI: 10.1073/pnas.1821120116
PMID: 30962382

Elevation in Plasma tRNA Fragments Precede Seizures in Human Epilepsy.
J Clin Invest.  2019 Apr; 129(7):2946-2951
DOI: 10.1172/JCI126346
PMID: 31039137

Exosomal tRNA-derived Small RNA as a Promising Biomarker for Cancer Diagnosis.
Mol Cancer.  2019 Apr; 18(1):74
DOI: 10.1186/s12943-019-1000-8
PMID: 30940133

Role of Host tRNAs and aminoacyl-tRNA Synthetases in Retroviral Replication.
J Biol Chem.  2019 Apr; 294(14):5352-5364
DOI: 10.1074/jbc.REV118.002957
PMID: 30700559

The Function of Non-Coding RNAs in Lung Cancer Tumorigenesis.
Cancers (Basel).  2019 Apr; 11(5):605
DOI: 10.3390/cancers11050605
PMID: 31052265

Limited Differential Expression of miRNAs and Other Small RNAs in LPS-stimulated Human Monocytes.
PLoS One.  2019 Mar; 14(3):e0214296
DOI: 10.1371/journal.pone.0214296
PMID: 30908559

Systematic Analysis of tRNA-Derived Small RNAs Reveals Novel Potential Therapeutic Targets of Traditional Chinese Medicine (Buyang-Huanwu-Decoction) on Intracerebral Hemorrhage.
Int J Biol Sci.  2019 Mar; 15(4):895-908
DOI: 10.7150/ijbs.29744
PMID: 30906219

Transfer RNA Demethylase ALKBH3 Promotes Cancer Progression via Induction of tRNA-derived Small RNAs.
Nucleic Acids Res.  2019 Mar; 47(5):2533-2545
DOI: 10.1093/nar/gky1250
PMID: 30541109

Transgenerational Response to Heat Stress in the Form of Differential Expression of Noncoding RNA Fragments in Brassica rapa Plants.
Plant Genome.  2019 Mar; 12(1)
DOI: 10.3835/plantgenome2018.04.0022
PMID: 30951085

tRNAs and tRNA Fragments as Modulators of Cardiac and Skeletal Muscle Function.
Biochim Biophys Acta Mol Cell Res.  2019 Mar; 1867(3):118465
DOI: 10.1016/j.bbamcr.2019.03.012
PMID: 30943428

tsRNAs: The Swiss Army Knife for Translational Regulation.
Trends Biochem Sci.  2019 Mar; 44(3):185-189
DOI: 10.1016/j.tibs.2018.09.007
PMID: 30297206

Functional Characterization of RNA Fragments Using High-Throughput Interactome Screening.
J Proteomics.  2019 Feb; 193:173-183
DOI: 10.1016/j.jprot.2018.10.007
PMID: 30339940

Metazoan tsRNAs: Biogenesis, Evolution and Regulatory Functions.
Noncoding RNA.  2019 Feb; 5(1):18
DOI: 10.3390/ncrna5010018
PMID: 30781726

The Influence of Paternal Diet on sncRNA-mediated Epigenetic Inheritance.
Mol Genet Genomics.  2019 Feb; 294(1):1-11
DOI: 10.1007/s00438-018-1492-8
PMID: 30229293

Translation Regulation in Skin Cancer From a tRNA Point of View.
Epigenomics.  2019 Feb; 11(2):215-245
DOI: 10.2217/epi-2018-0176
PMID: 30565492

tRNA deamination by ADAT requires substrate-specific recognition mechanisms and can be inhibited by tRFs.
RNA.  2019 Feb; 25(5):607-619
DOI: 10.1261/rna.068189.118
PMID: 30737359

A tRNA half modulates translation as stress response in Trypanosoma brucei.
Nat Commun.  2019 Jan; 10(1):118
DOI: 10.1038/s41467-018-07949-6
PMID: 30631057

Genome-wide Identification and Characterization of Transfer RNA-derived Small RNAs in Plasmodium Falciparum.
Parasit Vectors.  2019 Jan; 12(1):36
DOI: 10.1186/s13071-019-3301-6
PMID: 30646930

Identification of tRNA-derived ncRNAs in TCGA and NCI-60 Panel Cell Lines and Development of the Public Database tRFexplorer.
Database (Oxford).  2019 Jan; 2019:baz115
DOI: 10.1093/database/baz115
PMID: 31735953

Plant RNases T2, but not Dicer-like proteins, are major players of tRNA-derived fragments biogenesis.
Nucleic Acids Res.  2019 Jan; 47(2):941-952
DOI: 10.1093/nar/gky1156
PMID: 30462257

tiRNAs & tRFs Biogenesis and Regulation of Diseases: A Review.
Curr Med Chem.  2019 Jan; 26(31):5849-5861
DOI: 10.2174/0929867326666190124123831
PMID: 30678615

Molecules Derived From tRNA and snoRNA: Entering the Degradome Pool.
Biomed Pharmacother.  2018 Dec; 108:36-42
DOI: 10.1016/j.biopha.2018.09.017
PMID: 30216797

Selective Export Into Extracellular Vesicles and Function of tRNA Fragments During T Cell Activation.
Cell Rep.  2018 Dec; 25(12):3356-3370
DOI: 10.1016/j.celrep.2018.11.073
PMID: 30566862

Transcriptional and Small RNA Responses of the White Mold Fungus Sclerotinia sclerotiorum to Infection by a Virulence-Attenuating Hypovirus.
Viruses.  2018 Dec; 10(12):713
DOI: 10.3390/v10120713
PMID: 30558121

tRNA-Derived Small RNAs: Biogenesis, Modification, Function and Potential Impact on Human Disease Development.
Genes (Basel).  2018 Dec; 9(12):607
DOI: 10.3390/genes9120607
PMID: 30563140

A tRNA-derived RNA Fragment Plays an Important Role in the Mechanism of Arsenite -Induced Cellular Responses.
Sci Rep.  2018 Nov; 8(1):16838
DOI: 10.1038/s41598-018-34899-2
PMID: 30442959

Presence and diagnostic value of circulating tsncRNA for ovarian tumor.
Mol Cancer.  2018 Nov; 17(1):163
DOI: 10.1186/s12943-018-0910-1
PMID: 30466461

Transfer RNA-derived fragments and tRNA halves: biogenesis, biological functions and their roles in diseases.
J Mol Med (Berl).  2018 Nov; 96(11):1167-1176
DOI: 10.1007/s00109-018-1693-y
PMID: 30232504

tRNA-halves are prognostic biomarkers for patients with prostate cancer.
Urol Oncol.  2018 Nov; 36(11):503.e1-503.e7
DOI: 10.1016/j.urolonc.2018.08.003
PMID: 30209018

Ambient Temperature Regulates the Expression of a Small Set of sRNAs Influencing Plant Development Through NF-YA2 and YUC2.
Plant Cell Environ.  2018 Oct; 41(10):2404-2417
DOI: 10.1111/pce.13355
PMID: 29856891

Human tRNA-Derived Small RNAs Modulate Host-Oral Microbial Interactions.
J Dent Res.  2018 Oct; 97(11):1236-1243
DOI: 10.1177/0022034518770605
PMID: 29702004

Identification of tRNA-derived small noncoding RNAs as potential biomarkers for prediction of recurrence in triple-negative breast cancer.
Cancer Med.  2018 Oct; 7(10):5130-5144
DOI: 10.1002/cam4.1761
PMID: 30239174

Large Differences in Small RNA Composition Between Human Biofluids.
Cell Rep.  2018 Oct; 25(5):1346-1358
DOI: 10.1016/j.celrep.2018.10.014
PMID: 30380423

Queuosine Modification Protects Cognate tRNAs Against Ribonuclease Cleavage.
RNA.  2018 Oct; 24(10):1305-1313
DOI: 10.1261/rna.067033.118
PMID: 29970597

Tie-Break: Host and Retrotransposons Play tRNA.
Trends Cell Biol.  2018 Oct; 28(10):793-806
DOI: 10.1016/j.tcb.2018.05.006
PMID: 29934075

Dimerization Confers Increased Stability to Nucleases in 5' Halves From Glycine and Glutamic Acid tRNAs.
Nucleic Acids Res.  2018 Sep; 46(17):9081-9093
DOI: 10.1093/nar/gky495
PMID: 29893896

The role of RNA modifications in the regulation of tRNA cleavage.
FEBS Lett.  2018 Sep; 592(17):2828-2844
DOI: 10.1002/1873-3468.13205
PMID: 30058219

Transfer RNA-derived fragments as potential exosome tRNA-derived fragment biomarkers for osteoporosis.
Int J Rheum Dis.  2018 Sep; 21(9):1659-1669
DOI: 10.1111/1756-185X.13346
PMID: 30345646

Human Angiogenin Is a Potent Cytotoxin in the Absence of Ribonuclease Inhibitor.
RNA.  2018 Aug ; 24(8):1018-1027
DOI: 10.1261/rna.065516.117
PMID: 29748193

tRNA fragments (tRFs) guide Ago to regulate gene expression post-transcriptionally in a Dicer-independent manner.
RNA.  2018 Aug; 24(8):1093-1105
DOI: 10.1261/rna.066126.118
PMID: 29844106

tRNA-Derived Fragments as Novel Predictive Biomarkers for Trastuzumab-Resistant Breast Cancer.
Cell Physiol Biochem.  2018 Aug; 49(2):419-431
DOI: 10.1159/000492977
PMID: 30153663

A Novel Class of tRNA-Derived Small Non-Coding RNAs Respond to Myocardial Hypertrophy and Contribute to Intergenerational Inheritance.
Biomolecules.  2018 Jul; 8(3):54
DOI: 10.3390/biom8030054
PMID: 30012983

Association of Transfer RNA Fragments in White Blood Cells With Antibody Response to Bovine Leukemia Virus in Holstein Cattle.
Front Genet.  2018 Jul; 0.538888889
DOI: 10.3389/fgene.2018.00236
PMID: 30023000

Heterogeneity and Interplay of the Extracellular Vesicle Small RNA Transcriptome and Proteome.
Sci Rep.  2018 Jul; 8(1):10813
DOI: 10.1038/s41598-018-28485-9
PMID: 30018314

Drosophila tsRNAs preferentially suppress general translation machinery via antisense pairing and participate in cellular starvation response.
Nucleic Acids Res.  2018 Jun; 46(10):5250-5268
DOI: 10.1093/nar/gky189
PMID: 29548011

Small Non-Coding RNA Landscape Is Modified by GPAT2 Silencing in MDA-MB-231 Cells.
Oncotarget.  2018 Jun; 9(46):28141-28154
DOI: 10.18632/oncotarget.25582
PMID: 29963267

Transfer RNA-derived fragments target and regulate ribosome-associated aminoacyl-transfer RNA synthetases.
Biochim Biophys Acta Gene Regul Mech.  2018 Jun; S1874-9399(17)30380-2
DOI: 10.1016/j.bbagrm.2018.06.001
PMID: 29883755

Distribution of ncRNAs Expression Across Hypothalamic-Pituitary-Gonadal Axis in Capra Hircus.
BMC Genomics.  2018 May; 19(1):417
DOI: 10.1186/s12864-018-4767-x
PMID: 29848285

Early Life Diet Conditions the Molecular Response to Post-Weaning Protein Restriction in the Mouse.
BMC Biol.  2018 May; 16(1):51
DOI: 10.1186/s12915-018-0516-5
PMID: 29720174

Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells.
Cell.  2018 May ; 173(5):1204-1216
DOI: 10.1016/j.cell.2018.03.008
PMID: 29628141

Tackling Tumors With Small RNAs Derived From Transfer RNA.
N Engl J Med.  2018 May; 378(19):1842-1843
DOI: 10.1056/NEJMcibr1716989
PMID: 29742367

The Dysregulation of tRNAs and tRNA Derivatives in Cancer.
J Exp Clin Cancer Res.  2018 May; 37(1):101
DOI: 10.1186/s13046-018-0745-z
PMID: 29743091

tRNA-Derived Small RNA: A Novel Regulatory Small Non-Coding RNA.
Genes.  2018 May ; 9(5):246
DOI: 10.3390/genes9050246
PMID: 29748504

SPORTS1.0: A Tool for Annotating and Profiling Non-coding RNAs Optimized for rRNA- And tRNA-derived Small RNAs.
Genomics Proteomics Bioinformatics.  2018 Apr; 16(2):144-151
DOI: 10.1016/j.gpb.2018.04.004
PMID: 29730207

tRNA-derived small non-coding RNAs in human disease.
Cancer Lett.  2018 Apr; 419:1-7
DOI: 10.1016/j.canlet.2018.01.015
PMID: 29337107

Association of Circulating Transfer RNA fragments with antibody response to Mycoplasma bovis in beef cattle.
BMC Vet Res.  2018 Mar; 14(1):89
DOI: 10.1186/s12917-018-1418-z
PMID: 29534724

Profiles of miRNA Isoforms and tRNA Fragments in Prostate Cancer.
Sci Rep.  2018 Mar; 8(1):5314
DOI: 10.1038/s41598-018-22488-2
PMID: 29593348

Race Disparities in the Contribution of miRNA Isoforms and tRNA-Derived Fragments to Triple-Negative Breast Cancer.
Cancer Res.  2018 Mar; 78(5):1140-1154
DOI: 10.1158/0008-5472.CAN-17-1947
PMID: 29229607

5'-tRNA Halves Are Dysregulated in Clear Cell Renal Cell Carcinoma.
J Urol.  2018 Feb; 199(2):378-383
DOI: 10.1016/j.juro.2017.07.082
PMID: 28765068

Angiogenin Prevents Progranulin A9D Mutation-Induced Neuronal-Like Cell Apoptosis Through Cleaving tRNAs Into tiRNAs.
Mol Neurobiol.  2018 Feb; 55(2):1338-1351
DOI: 10.1007/s12035-017-0396-7
PMID: 28127696

Data Mining of Small RNA-Seq Suggests an Association Between Prostate Cancer and Altered Abundance of 5' Transfer RNA Halves in Seminal Fluid and Prostatic Tissues.
Biomark Cancer.  2018 Feb; 10:1179299X18759545
DOI: 10.1177/1179299X18759545
PMID: 29497340

Fine-Tuning of Gene Expression by tRNA-Derived Fragments during Abiotic Stress Signal Transduction.
Int J Mol Sci.  2018 Feb; 19(2):518
DOI: 10.3390/ijms19020518
PMID: 29419808

Roles of tRNA-derived Fragments in Human Cancers.
Cancer Lett.  2018 Feb; 414:16-25
DOI: 10.1016/j.canlet.2017.10.031
PMID: 29107107

Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin.
Data Brief.  2018 Feb; 17:397-400
DOI: 10.1016/j.dib.2018.01.050
PMID: 29876408

Transfer RNA-derived small RNAs in plants.
Sci China Life Sci.  2018 Feb; 61(2):155-161
DOI: 10.1007/s11427-017-9167-5
PMID: 29170889

tRNA-derived Small RNAs: New Players in Genome Protection Against Retrotransposons.
RNA Biol.  2018 Feb; 15(2):170-175
DOI: 10.1080/15476286.2017.1403000
PMID: 29120263

Accurate Profiling and Quantification of tRNA Fragments from RNA-Seq Data: A Vade Mecum for MINTmap.
Methods Mol Biol.  2018 Jan; 1680:237-255
DOI: 10.1007/978-1-4939-7339-2_16
PMID: 29030853

MINTbase v2.0: a comprehensive database for tRNA-derived fragments that includes nuclear and mitochondrial fragments from all The Cancer Genome Atlas projects.
Nucleic Acids Res.  2018 Jan; 46(D1):D152-D159
DOI: 10.1093/nar/gkx1075
PMID: 29186503

Malaria Infected Red Blood Cells Release Small Regulatory RNAs Through Extracellular Vesicles.
Sci Rep.  2018 Jan; 8(1):884
DOI: 10.1038/s41598-018-19149-9
PMID: 29343745

Multifaceted functional implications of an endogenously expressed tRNA fragment in the vector mosquito Aedes aegypti.
PLoS Negl Trop Dis.  2018 Jan; 12(1):e0006186
DOI: 10.1371/journal.pntd.0006186
PMID: 29364883

Novel Molecules lncRNAs, tRFs and circRNAs Deciphered From Next-Generation sequencing/RNA Sequencing: Computational Databases and Tools.
Brief Funct Genomics.  2018 Jan; 17(1):15-25
DOI: 10.1093/bfgp/elx013
PMID: 28637169

PtRFdb: a database for plant transfer RNA-derived fragments.
Database (Oxford).  2018 Jan; 2018:bay063
DOI: 10.1093/database/bay063
PMID: 29939244

The Emerging Complexity of the tRNA World: Mammalian tRNAs Beyond Protein Synthesis.
Nat Rev Mol Cell Biol.  2018 Jan; 19(1):45-58
DOI: 10.1038/nrm.2017.77
PMID: 28875994

tRex: A Web Portal for Exploration of tRNA-Derived Fragments in Arabidopsis thaliana.
Plant Cell Physiol.  2018 Jan; 59(1):e1
DOI: 10.1093/pcp/pcx173
PMID: 29145635

A Tale of Three RNAs in Mitochondria: tRNA, tRNA Derived Fragments and mitomiRs.
J Theor Biol.  2017 Dec; 435:42-49
DOI: 10.1016/j.jtbi.2017.09.002
PMID: 28888947

A transfer-RNA-derived small RNA regulates ribosome biogenesis.
Nature.  2017 Dec; 552(7683):57-62
DOI: 10.1038/nature25005
PMID: 29186115

Differentially Expressed tRNA-Derived Small RNAs Co-Sediment Primarily with Non-Polysomal Fractions in Drosophila.
Genes.  2017 Nov; 8(11):333
DOI: 10.3390/genes8110333
PMID: 29156628

Effects of G-quadruplex Topology on Translational Inhibition by tRNA Fragments in Mammalian and Plant Systems in Vitro.
Int J Biochem Cell Biol.  2017 Nov; 92:148-154
DOI: 10.1016/j.biocel.2017.10.001
PMID: 28989078

tRF-Leu-CAG promotes cell proliferation and cell cycle in non-small cell lung cancer.
Chem Biol Drug Des.  2017 Nov; 90(5):730-738
DOI: 10.1111/cbdd.12994
PMID: 28378898

tRNAs as Primers and Inhibitors of Retrotransposons.
Mob Genet Elements.  2017 Nov; 7(5):1-6
DOI: 10.1080/2159256X.2017.1393490
PMID: 29201533

tsRNAs: new players in mammalian retrotransposon control.
Cell Res.  2017 Nov; 27(11):1307-1308
DOI: 10.1038/cr.2017.109
PMID: 28840860

A tRNA-derived fragment competes with mRNA for ribosome binding and regulates translation during stress.
RNA Biol.  2017 Oct; 14(10):1364-1373
DOI: 10.1080/15476286.2016.1257470
PMID: 27892771

Identification of Functional Tetramolecular RNA G-quadruplexes Derived From Transfer RNAs.
Nat Commun.  2017 Oct; 8(1):1127
DOI: 10.1038/s41467-017-01278-w
PMID: 29066746

A tRNA fragment, tRF5-Glu, regulates BCAR3 expression and proliferation in ovarian cancer cells.
Oncotarget.  2017 Sep; 8(56):95377-95391
DOI: 10.18632/oncotarget.20709
PMID: 29221134

Identification of Metastasis-Associated microRNAs in Serum From Rectal Cancer Patients.
Oncotarget.  2017 Sep; 8(52):90077-90089
DOI: 10.18632/oncotarget.21412
PMID: 29163812

MicroRNAs and tRNA-derived Fragments Predict the Transformation of Myelodysplastic Syndromes to Acute Myeloid Leukemia.
Leuk Lymphoma.  2017 Sep; 58(9):1-15
DOI: 10.1080/10428194.2016.1272680
PMID: 28084850

The Biogenesis Pathway of tRNA-derived piRNAs in Bombyx Germ Cells.
Nucleic Acids Res.  2017 Sep; 45(15):9108-9120
DOI: 10.1093/nar/gkx537
PMID: 28645172

The RNA methyltransferase Dnmt2 methylates DNA in the structural context of a tRNA.
RNA Biol.  2017 Sep; 14(9):1241-1251
DOI: 10.1080/15476286.2016.1236170
PMID: 27819523

Role of the tRNA-Derived Small RNAs in Cancer: New Potential Biomarkers and Target for Therapy.
Adv Cancer Res.  2017 Aug; 135:173-187
DOI: 10.1016/bs.acr.2017.06.007
PMID: 28882222

Identification of Two Novel Functional tRNA-derived Fragments Induced in Response to Respiratory Syncytial Virus Infection.
J Gen Virol.  2017 Jul; 98(7):1600-1610
DOI: 10.1099/jgv.0.000852
PMID: 28708049

tRNA Derived smallRNAs: smallRNAs Repertoire Has Yet to Be Decoded in Plants.
Front Plant Sci.  2017 Jul; 1.14375
DOI: 10.3389/fpls.2017.01167
PMID: 28791028

tsRNA signatures in cancer.
Proc Natl Acad Sci U S A.  2017 Jul; 114(30):8071-8076
DOI: 10.1073/pnas.1706908114
PMID: 28696308

Discovery and function of transfer RNA-derived fragments and their role in disease.
Wiley Interdiscip Rev RNA.  2017 Sep; 8(5)
DOI: 10.1002/wrna.1423
PMID: 28608481

LTR-Retrotransposon Control by tRNA-Derived Small RNAs.
Cell.  2017 Jun; 170(1):61-71
DOI: 10.1016/j.cell.2017.06.013
PMID: 28666125

Non-Coding RNAs Are Differentially Expressed by Nocardia Brasiliensis in Vitro and in Experimental Actinomycetoma.
Open Microbiol J.  2017 Jun; 11:112-125
DOI: 10.2174/1874285801711010112
PMID: 28839491

tRF/miR-1280 Suppresses Stem Cell-like Cells and Metastasis in Colorectal Cancer.
Cancer Res.  2017 Jun; 77(12):3194-3206
DOI: 10.1158/0008-5472.CAN-16-3146
PMID: 28446464

Exercise Alters Mouse Sperm Small Noncoding RNAs and Induces a Transgenerational Modification of Male Offspring Conditioned Fear and Anxiety.
Transl Psychiatry.  2017 May; 7(5):e1114
DOI: 10.1038/tp.2017.82
PMID: 28463242

Small Non-Coding RNA and Cancer.
Carcinogenesis.  2017 May; 38(5):485-491
DOI: 10.1093/carcin/bgx026
PMID: 28449079

tRNA-derived Small RNAs Target Transposable Element Transcripts.
Nucleic Acids Res.  2017 May; 45(9):5142-5152
DOI: 10.1093/nar/gkx103
PMID: 28335016

Differential Processing of Small RNAs During Endoplasmic Reticulum Stress.
Sci Rep.  2017 Apr; 7:46080
DOI: 10.1038/srep46080
PMID: 28452371

The nuclear and organellar tRNA-derived RNA fragment population in Arabidopsis thaliana is highly dynamic.
Nucleic Acids Res.  2017 Apr; 45(6):3460-3472
DOI: 10.1093/nar/gkw1122
PMID: 27899576

Identification of Unknown RNA Partners Using MAPS.
Methods.  2017 Mar; 117:28-34
DOI: 10.1016/j.ymeth.2016.11.011
PMID: 27876680

Total Extracellular Small RNA Profiles From Plasma, Saliva, and Urine of Healthy Subjects.
Sci Rep.  2017 Mar; 7:44061
DOI: 10.1038/srep44061
PMID: 28303895

5'-Terminal Nucleotide Variations in Human Cytoplasmic tRNAHisGUG and Its 5'-halves.
RNA.  2017 Feb; 23(2):161-168
DOI: 10.1261/rna.058024.116
PMID: 27879434

Defining the Purity of Exosomes Required for Diagnostic Profiling of Small RNA Suitable for Biomarker Discovery.
RNA Biol.  2017 Feb; 14(2):245-258
DOI: 10.1080/15476286.2016.1270005
PMID: 28005467

Identification of Urinary Exosomal Noncoding RNAs as Novel Biomarkers in Chronic Kidney Disease.
RNA.  2017 Feb; 23(2):142-152
DOI: 10.1261/rna.058834.116
PMID: 27872161

MINTmap: Fast and Exhaustive Profiling of Nuclear and Mitochondrial tRNA Fragments From Short RNA-seq Data.
Sci Rep.  2017 Feb; 7:41184
DOI: 10.1038/srep41184
PMID: 28220888

tRNA-Derived RNA Fragments Associate with Human Multisynthetase Complex (MSC) and Modulate Ribosomal Protein Translation.
J Proteome Res.  2017 Feb; 16(2):413-420
DOI: 10.1021/acs.jproteome.6b00267
PMID: 27936807

Cloaked Dagger: tRNA Slicing by an Unlikely Culprit.
RNA Biol.  2017 Jan; 14(1):15-19.
DOI: 10.1080/15476286.2016.1255396
PMID: 27841735

Comprehensive Evaluation of Extracellular Small RNA Isolation Methods From Serum in High Throughput Sequencing.
BMC Genomics.  2017 Jan; 18(1):50
DOI: 10.1186/s12864-016-3470-z
PMID: 28061744

Computational Approaches to tRNA-Derived Small RNAs.
Noncoding RNA.  2017 Jan; 3(1):2
DOI: 10.3390/ncrna3010002
PMID: 29657274

Genome-wide identification and characterization of tRNA-derived RNA fragments in land plants.
Plant Mol Biol.  2017 Jan; 93(1-2):35-48
DOI: 10.1007/s11103-016-0545-9
PMID: 27681945

Small RNA Modifications: Integral to Function and Disease.
Trends Mol Med.  2016 Dec; 22(12):1025-1034
DOI: 10.1016/j.molmed.2016.10.009
PMID: 27840066

The tRNA-Derived Small RNAs Regulate Gene Expression Through Triggering Sequence-Specific Degradation of Target Transcripts in the Oomycete Pathogen Phytophthora sojae.
Front Plant Sci.  2016 Dec; 1.6375
DOI: 10.3389/fpls.2016.01938
PMID: 28066490

Dynamics of tRNA Fragments and Their Targets in Aging Mammalian Brain.
F1000Res.  2016 Nov; 5:ISCB Comm J-2758
DOI: 10.12688/f1000research.10116.1
PMID: 28105302

Identification of aberrant tRNA-halves expression patterns in clear cell renal cell carcinoma.
Sci Rep.  2016 Nov; 6:37158
DOI: 10.1038/srep37158
PMID: 27883021

The Widespread Occurrence of tRNA-derived Fragments in Saccharomyces cerevisiae.
FEBS Open Bio.  2016 Oct; 6(12):1186-1200
DOI: 10.1002/2211-5463.12127
PMID: 28203519

Sperm tsRNAs and Acquired Metabolic Disorders.
J Endocrinol.  2016 Sep; 230(3):F13-8
DOI: 10.1530/JOE-16-0185
PMID: 27340033

tRNA-derived Short RNAs Bind to Saccharomyces Cerevisiae Ribosomes in a Stress-Dependent Manner and Inhibit Protein Synthesis in Vitro.
FEMS Yeast Res.  2016 Sep; 16(6):fow077
DOI: 10.1093/femsyr/fow077
PMID: 27609601

Biogenesis and Function of Transfer RNA-Related Fragments (tRFs).
Trends Biochem Sci.  2016 Aug; 41(8):679-689
DOI: 10.1016/j.tibs.2016.05.004
PMID: 27263052

From tRNA to miRNA: RNA-folding Contributes to Correct Entry Into Noncoding RNA Pathways.
FEBS Lett.  2016 Aug; 590(15):2354-63
DOI: 10.1002/1873-3468.12294
PMID: 27397696

MINTbase: a framework for the interactive exploration of mitochondrial and nuclear tRNA fragments.
Bioinformatics.  2016 Aug; 32(16):2481-9
DOI: 10.1093/bioinformatics/btw194
PMID: 27153631

YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression.
Nucleic Acids Res.  2016 Aug; 44(14):6949-60
DOI: 10.1093/nar/gkw418
PMID: 27174937

The Lupus Autoantigen La Prevents Mis-channeling of tRNA Fragments into the Human MicroRNA Pathway.
Mol Cell.  2016 Jul; 63(1):110-24
DOI: 10.1016/j.molcel.2016.05.026
PMID: 27345152

tRF2Cancer: A web server to detect tRNA-derived small RNA fragments (tRFs) and their expression in multiple cancers.
Nucleic Acids Res.  2016 Jul; 44(W1):W185-93
DOI: 10.1093/nar/gkw414
PMID: 27179031

Transfer RNA Derived Small RNAs Targeting Defense Responsive Genes Are Induced During Phytophthora Capsici Infection in Black Pepper (Piper Nigrum L.).
Front Plant Sci.  2016 Jun; 0.824305556
DOI: 10.3389/fpls.2016.00767
PMID: 27313593

Transfer RNA-derived Small RNAs in the Cancer Transcriptome.
Pflugers Arch.  2016 Jun; 468(6):1041-7
DOI: 10.1007/s00424-016-1822-9
PMID: 27095039

Dysregulation of a family of short noncoding RNAs,tsRNAs, in human cancer.
Proc Natl Acad Sci U S A.  2016 May; 113(18):5071-6
DOI: 10.1073/pnas.1604266113
PMID: 27071132

A comprehensive repertoire of tRNA-derived fragments in prostate cancer.
Oncotarget.  2016 Apr; 7(17):24766-77
DOI: 10.18632/oncotarget.8293
PMID: 27015120

RNA Fragments Mimicking tRNA Analogs Interact With Cytochrome C.
Mol Biol Rep.  2016 Apr ; 43(4):295-304
DOI: 10.1007/s11033-016-3954-6
PMID: 26892782

tRFs: miRNAs in disguise.
Gene.  2016 Apr; 579(2):133-8
DOI: 10.1016/j.gene.2015.12.058
PMID: 26743126

tRNA Fragments: Novel Players in Intergenerational Inheritance.
Cell Res.  2016 Apr ; 26(4):395-6
DOI: 10.1038/cr.2016.24
PMID: 26902286

Characterization of Small RNAs Derived From tRNAs, rRNAs and snoRNAs and Their Response to Heat Stress in Wheat Seedlings.
PLoS One.  2016 Mar; 11(3):e0150933
DOI: 10.1371/journal.pone.0150933
PMID: 26963812

Consequential Considerations When Mapping tRNA Fragments.
BMC Bioinformatics.  2016 Mar; 0.79375
DOI: 10.1186/s12859-016-0921-0
PMID: 26961774

Transferring Fragments of Paternal Metabolism to the Offspring.
Cell Metab.  2016 Mar; 23(3):401-2
DOI: 10.1016/j.cmet.2016.02.014
PMID: 26959182

IL-4 Inhibits the Biogenesis of an Epigenetically Suppressive PIWI-Interacting RNA To Upregulate CD1a Molecules on Monocytes/Dendritic Cells.
J Immunol.  2016 Feb; 196(4):1591-603
DOI: 10.4049/jimmunol.1500805
PMID: 26755820

tRNA-Derived Small Non-Coding RNAs in Response to Ischemia Inhibit Angiogenesis.
Sci Rep.  2016 Feb; 6:20850
DOI: 10.1038/srep20850
PMID: 26865164

Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals.
Science.  2016 Jan; 351(6271):391-396
DOI: 10.1126/science.aad6780
PMID: 26721685

Sperm RNA Fragments Modify Offspring Metabolism.
Science.  2016 Jan; 351(6268):13
DOI: 10.1126/science.351.6268.13
PMID: 26721982

Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder.
Science.  2016 Jan; 351(6271):397-400
DOI: 10.1126/science.aad7977
PMID: 26721680

Conserved and Highly Expressed tRNA Derived Fragments in Zebrafish.
BMC Mol Biol.  2015 Dec; 16:22
DOI: 10.1186/s12867-015-0050-8
PMID: 26694924

The Many Virtues of tRNA-derived Stress-induced RNAs (tiRNAs): Discovering Novel Mechanisms of Stress Response and Effect on Human Health.
J Biol Chem.  2015 Dec; 290(50):29761-8
DOI: 10.1074/jbc.R115.694661
PMID: 26463210

tRNA-Derived Fragments (tRFs): Emerging New Roles for an Ancient RNA in the Regulation of Gene Expression.
Life (Basel).  2015 Dec; 5(4):1638-51
DOI: 10.3390/life5041638
PMID: 26703738

SHOT-RNAs: A Novel Class of tRNA-derived Functional RNAs Expressed in Hormone-Dependent Cancers.
Mol Cell Oncol.  2015 Nov; 3(2):e1079672
DOI: 10.1080/23723556.2015.1079672
PMID: 27308603

Respiratory Syncytial Virus Utilizes a tRNA Fragment to Suppress Antiviral Responses Through a Novel Targeting Mechanism.
Mol Ther.  2015 Oct; 23(10):1622-9
DOI: 10.1038/mt.2015.124
PMID: 26156244

Age-driven modulation of tRNA-derived fragments in Drosophila and their potential targets.
Biol Direct.  2015 Sep; 10:51
DOI: 10.1186/s13062-015-0081-6
PMID: 26374501

Dissecting tRNA-derived fragment complexities using personalized transcriptomes reveals novel fragment classes and unexpected dependencies.
Oncotarget.  2015 Sep; 6(28):24797-822
DOI: 10.18632/oncotarget.4695
PMID: 26325506

Transfer RNA detection by small RNA deep sequencing and disease association with myelodysplastic syndromes.
BMC Genomics.  2015 Sep; 1.171527778
DOI: 10.1186/s12864-015-1929-y
PMID: 26400237

tRNA-Derived Short Non-coding RNA as Interacting Partners of Argonaute Proteins.
Gene Regul Syst Bio.  2015 Sep; 9:27-33
DOI: 10.4137/GRSB.S29411
PMID: 26401098

Characterization of circulating transfer RNA-derived RNA fragments in cattle.
Front Genet.  2015 Aug; 0.438194444
DOI: 10.3389/fgene.2015.00271
PMID: 26379699

Circulating small non-coding RNA signature in head and neck squamous cell carcinoma.
Oncotarget.  2015 Aug; 6(22):19246-63
DOI: 10.18632/oncotarget.4266
PMID: 26057471

Profiling of the small RNA populations in human testicular germ cell tumors shows global loss of piRNAs.
Mol Cancer.  2015 Aug; 0.689583333
DOI: 10.1186/s12943-015-0411-4
PMID: 26265322

Precise mapping and dynamics of tRNA-derived fragments (tRFs) in the development of Triops cancriformis (tadpole shrimp).
BMC Genet.  2015 Jul; 0.724305556
DOI: 10.1186/s12863-015-0245-5
PMID: 26168920

Sex hormone-dependent tRNA halves enhance cell proliferation in breast and prostate cancers.
Proc Natl Acad Sci U S A.  2015 Jul; 112(29):E3816-25
DOI: 10.1073/pnas.1510077112
PMID: 26124144

Breast Cancer-Specific miR Signature Unique to Extracellular Vesicles includes "microRNA-like" tRNA Fragments.
Mol Cancer Res.  2015 May; 13(5):891-901
DOI: 10.1158/1541-7786.MCR-14-0533
PMID: 25722304

Endogenous tRNA-Derived Fragments Suppress Breast Cancer Progression via YBX1 Displacement.
Cell.  2015 May; 161(4):790-802
DOI: 10.1016/j.cell.2015.02.053
PMID: 25957686

Small RNAs derived from tRNAs and rRNAs are highly enriched in exosomes from both old and new world Leishmania providing evidence for conserved exosomal RNA Packaging.
BMC Genomics.  2015 Mar; 16(1):151
DOI: 10.1186/s12864-015-1260-7
PMID: 25764986

5' tRNA Halves: The Next Generation of Immune Signaling Molecules.
Front Immunol.  2015 Feb; 0.301388889
DOI: 10.3389/fimmu.2015.00074
PMID: 25745425

Assessing the gene regulatory properties of Argonaute-bound small RNAs of diverse genomic origin.
Nucleic Acids Res.  2015 Jan; 43(1):470-81
DOI: 10.1093/nar/gku1242
PMID: 25452337

Disrupted tRNA Genes and tRNA Fragments: A Perspective on tRNA Gene Evolution.
Life (Basel).  2015 Jan; 5(1):321-31
DOI: 10.3390/life5010321
PMID: 25629271

Mining diverse small RNA species in the deep transcriptome.
Trends Biochem Sci.  2015 Jan; 40(1):4-7
DOI: 10.1016/j.tibs.2014.10.009
PMID: 25435401

Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C.
Sci Rep.  2015 Jan; 5.538194444
DOI: 10.1038/srep07675
PMID: 25567797

tRFdb: a database for transfer RNA fragments.
Nucleic Acids Res.  2015 Jan; 43(Database issue):D141-5
DOI: 10.1093/nar/gku1138
PMID: 25392422

Deep Sequencing of Serum Small RNAs Identifies Patterns of 5' tRNA Half and YRNA Fragment Expression Associated with Breast Cancer.
Biomark Cancer.  2014 Dec; 6:37-47
DOI: 10.4137/BIC.S20764
PMID: 25520563

Fragmentation of tRNA in Phytophthora infestans asexual life cycle stages and during host plant infection.
BMC Microbiology.  2014 Dec; 0.797222222
DOI: 10.1186/s12866-014-0308-1
PMID: 25492044

G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments.
Proc Natl Acad Sci U S A.  2014 Dec; 111(51):18201-6
DOI: 10.1073/pnas.1407361111
PMID: 25404306

tRNA fragments in human health and disease.
FEBS Lett.  2014 Nov; 588(23):4297-304
DOI: 10.1016/j.febslet.2014.09.001
PMID: 25220675

Meta-analysis of tRNA derived RNA fragments reveals that they are evolutionarily conserved and associate with AGO proteins to recognize specific RNA targets.
BMC biology.  2014 Oct; 0.554166667
DOI: 10.1186/s12915-014-0078-0
PMID: 25270025

Aberrant methylation of tRNAs links cellular stress to neuro developmental disorders.
The EMBO Journal.  2014 Sep; 33(18):2020-39
DOI: 10.15252/embj.201489282
PMID: 25063673

Both endo-siRNAs and tRNA-derived small RNAs are involved in the differentiation of primitive eukaryote Giardia lamblia.
Proc Natl Acad Sci U S A.  2014 Sep; 111(39):14159-64
DOI: 10.1073/pnas.1414394111
PMID: 25225396

The human Piwi protein Hiwi2 associates with tRNA-derived piRNAs in somatic cells.
Nucleic Acids Res.  2014 Aug; 42(14):8984-95
DOI: 10.1093/nar/gku620
PMID: 25038252

Angiogenin-cleaved tRNA halves interact with cytochrome c, protecting cells from apoptosis during osmotic stress.
Mol Cell Biol.  2014 Jul; 34(13):2450-63
DOI: 10.1128/MCB.00136-14
PMID: 24752898

Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions.
Nucleic Acids Res.  2014 Jun; 42(11):7290-304
DOI: 10.1093/nar/gku347
PMID: 24838567

Computational analysis, biochemical purification, and detection of tRNA-derived small RNA fragments.
Methods Mol Biol.  2014 May ; 1173:157-67
DOI: 10.1007/978-1-4939-0931-5_14
PMID: 24920368

Gene expression changes induced by Trypanosoma cruzi shed microvesicles in mammalian host cells: relevance of tRNA-derived halves.
Biomed Res Int.  2014 Apr; 2014:305239
DOI: 10.1155/2014/305239
PMID: 24812611

Small noncoding RNAs in cells transformed by human T-cell leukemia virus type 1: a role for a tRNA fragment as a primer for reverse transcriptase.
J Virol.  2014 Apr; 88(7):3612-22
DOI: 10.1128/JVI.02823-13
PMID: 24403582

Slicing tRNAs to boost functional ncRNA diversity.
RNA Biol.  2013 Dec; 10(12):1798-806
DOI: 10.4161/rna.27177
PMID: 24351723

Beyond microRNA--novel RNAs derived from small non-coding RNA and their implication in cancer.
Cancer Lett.  2013 Nov; 340(2):201-11
DOI: 10.1016/j.canlet.2012.11.058
PMID: 23376637

Links between the oncoprotein YB-1 and small non-coding RNAs in breast cancer.
PLoS One.  2013 Nov; 8(11):e80171
DOI: 10.1371/journal.pone.0080171
PMID: 24260353

Identification of stable, high copy number, medium-sized RNA degradation intermediates that accumulate in plants under non-stress conditions.
Plant Mol Biol.  2013 Oct; 83(3):191-204
DOI: 10.1007/s11103-013-0079-3
PMID: 23708952

RIP-seq of BmAgo2-associated small RNAs reveal various types of small non-coding RNAs in the silkworm, Bombyx mori.
BMC Genomics.  2013 Sep; 1.042361111
DOI: 10.1186/1471-2164-14-661
PMID: 24074203

5' tRNA halves are present as abundant complexes in serum, concentrated in blood cells, and modulated by aging and calorie restriction.
BMC Genomics.  2013 May; 0.790277778
DOI: 10.1186/1471-2164-14-298
PMID: 23638709

A deep analysis of the small non-coding RNA population in Schistosoma japonicum eggs.
PLoS One.  2013 May; 8(5):e64003
DOI: 10.1371/journal.pone.0064003
PMID: 23691136

Novel aspects of tRNA-derived small RNAs with potential impact in infectious diseases.
Advances in Bioscience and Biotechnology.  2013 May; 4(5A):17-25.
DOI: 10.4236/abb.2013.45A002

A comprehensive expression profile of microRNAs and other classes of non-coding small RNAs in barley under phosphorous-deficient and -sufficient conditions.
DNA Res.  2013 Apr; 20(2):109-25
DOI: 10.1093/dnares/dss037
PMID: 23266877

Small RNAs derived from the 5' end of tRNA can inhibit protein translation in human cells.
RNA Biol.  2013 Apr; 10(4):553-63
DOI: 10.4161/rna.24285
PMID: 23563448

tRNA modifications: necessary for correct tRNA-derived fragments during the recovery from stress.
Bioessays.  2013 Apr; 35(4):323-7
DOI: 10.1002/bies.201200158
PMID: 23315679

CLP1 links tRNA metabolism to progressive motor-neuron loss.
Nature.  2013 Mar; 495(7442):474-80
DOI: 10.1038/nature11923
PMID: 23474986

Description of plant tRNA-derived RNA fragments (tRFs) associated with argonaute and identification of their putative targets.
Biology Direct.  2013 Feb; 8:06
DOI: 10.1186/1745-6150-8-6
PMID: 23402430

Identification and functional characterization of tRNA-derived RNA fragments (tRFs) in respiratory syncytial virus infection.
Mol Ther.  2013 Feb; 21(2):368-79
DOI: 10.1038/mt.2012.237
PMID: 23183536

tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma.
Proc Natl Acad Sci U S A.  2013 Jan; 110(4):1404-9
DOI: 10.1073/pnas.1206761110
PMID: 23297232

Genome-wide identification and quantitative analysis of cleaved tRNA fragments induced by cellular stress.
J Biol Chem.  2012 Dec; 287(51):42708-25
DOI: 10.1074/jbc.M112.371799
PMID: 23086926

tRNA-derived fragments target the ribosome and function as regulatory non-coding RNA in Haloferax volcanii.
Archaea.  2012 Dec; 2012:260909
DOI: 10.1155/2012/260909
PMID: 23326205

A Tetrahymena Piwi bound to mature tRNA 3' fragments activates the exonuclease Xrn2 for RNA processing in the nucleus.
Mol Cell.  2012 Nov; 48(4):509-20
DOI: 10.1016/j.molcel.2012.09.010
PMID: 23084833

A novel class of tRNA-derived small RNAs extremely enriched in mature mouse sperm.
Cell Res.  2012 Nov; 22(11):1609-12
DOI: 10.1038/cr.2012.141
PMID: 23044802

Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions.
Nucleic Acids Res.  2012 Oct; 40(18):9272-85
DOI: 10.1093/nar/gks658
PMID: 22821563

Hints of tRNA-Derived Small RNAs Role in RNA Silencing Mechanisms.
Genes (Basel).  2012 Oct; 3(4):603-14
DOI: 10.3390/genes3040603
PMID: 24705078

Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi.
Mem Inst Oswaldo Cruz.  2012 Sep; 107(6):816-9
DOI: 10.1590/s0074-02762012000600018
PMID: 22990974

RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis.
Nat Struct Mol Biol.  2012 Sep; 19(9):900-5
DOI: 10.1038/nsmb.2357
PMID: 22885326

Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs.
Nucleic Acids Res.  2012 Aug; 40(14):6787-99
DOI: 10.1093/nar/gks307
PMID: 22492706

High throughput sequencing reveals a plethora of small RNAs including tRNA derived fragments in Haloferax volcanii.
RNA Biol.  2012 Jul; 9(7):1011-8
DOI: 10.4161/rna.20826
PMID: 22767255

Structure-Function Analysis of Rny1 in tRNA Cleavage and Growth Inhibition.
PLoS One.  2012 Jul; 7(7):e41111
DOI: 10.1371/journal.pone.0041111
PMID: 22829915

Several RNase T2 enzymes function in induced tRNA and rRNA turnover in the ciliate Tetrahymena.
Mol Biol Cell.  2012 Jan; 23(1):36-44
DOI: 10.1091/mbc.E11-08-0689
PMID: 22049026

Transfer RNA-derived fragments: origins, processing, and functions.
Wiley Interdiscip Rev RNA.  2011 Nov; 2(6):853-62
DOI: 10.1002/wrna.96
PMID: 21976287

Angiogenin-induced tRNA fragments inhibit translation initiation.
Mol Cell.  2011 Aug; 43(4):613-23
DOI: 10.1016/j.molcel.2011.06.022
PMID: 21855800

A novel class of heat-responsive small RNAs derived from the chloroplast genome of Chinese cabbage (Brassica rapa).
BMC Genomics.  2011 Jun; 0.700694444
DOI: 10.1186/1471-2164-12-289
PMID: 21639890

Diverse and tissue-enriched small RNAs in the plant pathogenic fungus, Magnaporthe oryzae.
BMC Genomics.  2011 Jun; 0.7
DOI: 10.1186/1471-2164-12-288
PMID: 21635781

Genome-wide discovery and analysis of microRNAs and other small RNAs from rice embryogenic callus.
RNA Biol.  2011 May; 8(3):538-47
DOI: 10.4161/rna.8.3.15199
PMID: 21525786

Deep-sequencing of human Argonaute-associated small RNAs provides insight into miRNA sorting and reveals Argonaute association with RNA fragments of diverse origin.
RNA Biol.  2011 Jan; 8(1):158-77
DOI: 10.4161/rna.8.1.14300
PMID: 21282978

A growth-essential Tetrahymena Piwi protein carries tRNA fragment cargo.
Genes Dev.  2010 Dec; 24(24):2742-7
DOI: 10.1101/gad.1996210
PMID: 21106669

Regulatory RNAs derived from transfer RNA?
RNA.  2010 Oct; 16(10):1865-9
DOI: 10.1261/rna.2266510
PMID: 20719919

A miRNA-tRNA mix-up: tRNA origin of proposed miRNA.
RNA Biol.  2010 Sep; 7(5):573-6
DOI: 10.4161/rna.7.4.13141
PMID: 20818168

tRNA biology charges to the front.
Genes Dev.  2010 Sep; 24(17):1832-60
DOI: 10.1101/gad.1956510
PMID: 20810645

RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage.
Genes Dev.  2010 Aug; 24(15):1590-5
DOI: 10.1101/gad.586710
PMID: 20679393

A population of tRNA-derived small RNAs is actively produced in Trypanosoma cruzi and recruited to specific cytoplasmic granules.
Mol Biochem Parasitol.  2010 Jun; 171(2):64-73
DOI: 10.1016/j.molbiopara.2010.02.003
PMID: 20156490

Abundance of tRNA-derived small RNAs in phosphate-starved Arabidopsis roots.
Plant Signal Behav.  2010 May; 5(5):537-9
DOI: 10.4161/psb.11029
PMID: 20404547

Deep sequencing of human nuclear and cytoplasmic small RNAs reveals an unexpectedly complex subcellular distribution of miRNAs and tRNA 3' trailers.
PLoS One.  2010 May; 5(5):e10563
DOI: 10.1371/journal.pone.0010563
PMID: 20498841

Angiogenin-induced tRNA-derived stress-induced RNAs promote stress-induced stress granule assembly.
J Biol Chem.  2010 Apr; 285(14):10959-68
DOI: 10.1074/jbc.M109.077560
PMID: 20129916

Human tRNA-derived small RNAs in the global regulation of RNA silencing.
RNA.  2010 Apr; 16(4):673-95
DOI: 10.1261/rna.2000810
PMID: 20181738

Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs.
RNA.  2009 Dec; 15(12):2147-60
DOI: 10.1261/rna.1738409
PMID: 19850906

Uncovering small RNA-mediated responses to phosphate deficiency in Arabidopsis by deep sequencing.
Plant Physiol.  2009 Dec; 151(4):2120-32
DOI: 10.1104/pp.109.147280
PMID: 19854858

A novel class of small RNAs: tRNA-derived RNA fragments (tRFs).
Genes Dev.  2009 Nov; 23(22):2639-49
DOI: 10.1101/gad.1837609
PMID: 19933153

Stressing Out over tRNA Cleavage.
Cell.  2009 Jul; 138(2):215-9
DOI: 10.1016/j.cell.2009.07.001
PMID: 19632169

Modulation of Gene Expression by Human Cytosolic tRNase Z through 5'-Half-tRNA.
PLoS One.  2009 Jun; 4(6):e5908
DOI: 10.1371/journal.pone.0005908
PMID: 19526060

The phloem-delivered RNA pool contains small noncoding RNAs and interferes with translation.
Plant Physiol.  2009 May; 150(1):378-87
DOI: 10.1104/pp.108.134767
PMID: 19261735

Angiogenin cleaves tRNA and promotes stress-induced translational repression.
J Cell Biol.  2009 Apr; 185(1):35-42
DOI: 10.1083/jcb.200811106
PMID: 19332886

The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress in Saccharomyces cerevisiae.
J Cell Biol.  2009 Apr; 185(1):43-50
DOI: 10.1083/jcb.200811119.
PMID: 19332891

Stress induces tRNA cleavage by angiogenin in mammalian cells.
FEBS Letters.  2009 Jan; 583(2):437-42
DOI: 10.1016/j.febslet.2008.12.043
PMID: 19114040

Stress-induced tRNA-derived RNAs: a novel class of small RNAs in the primitive eukaryote Giardia lamblia.
Nucleic Acids Res.  2008 Nov; 36(19):6048-55
DOI: 10.1093/nar/gkn596
PMID: 18820301

Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs.
Genes Dev.  2008 Oct; 22(20):2773-85
DOI: 10.1101/gad.1705308
PMID: 18923076

tRNA cleavage is a conserved response to oxidative stress in eukaryotes.
RNA.  2008 Oct; 14(10):2095-103
DOI: 10.1261/rna.1232808
PMID: 18719243

Hidden layers of human small RNAs.
BMC Genomics.  2008 Apr; 0.484027778
DOI: 10.1186/1471-2164-9-157
PMID: 18402656

Developmentally regulated cleavage of tRNAs in the bacterium Streptomyces coelicolor.
Nucleic Acids Res.  2008 Feb; 36(3):732-41
DOI: 10.1093/nar/gkm1096
PMID: 18084030

Starvation-induced cleavage of the tRNA anticodon loop in Tetrahymena thermophila.
J Biol Chem.  2005 Dec; 280(52):42744-9
DOI: 10.1074/jbc.M510356200
PMID: 16272149

A cytotoxic ribonuclease which specifically cleaves four isoaccepting arginine tRNAs at their anticodon loops.
Proc Natl Acad Sci U S A.  2000 Jul; 97(15):8278-83
DOI: 10.1073/pnas.140213797
PMID: 10880568

New role for tRNA and its fragment purified from human urinary bladder carcinoma conditioned medium: inhibition of endothelial cell growth.
J Cell Biochem.  1999 Nov; 76(1):109-17
DOI: 10.1002/(sici)1097-4644(20000101)76:1<109::aid-jcb11>3.0.co;2-k
PMID: 10581005

tRNA breakdown products as markers for cancer.
Cancer.  1979 Dec; 44(6):2120-3
DOI: 10.1002/1097-0142(197912)44:6<2120::aid-cncr2820440623>3.0.co;2-6
PMID: 509391